Peyronie's Disease

Peyronie’s disease is a connective tissue disorder that results in the growth of fibrous plaques in the soft tissue of the penis. Sometimes described as the result of trauma to the aging penis, Peyronie’s is estimated to affect anywhere from 5-10% of middle-aged men. It can cause pain, abnormal curvature, erectile dysfunction and penile shortening. The resulting curvature can often be significant and in some men can even make intercourse impossible.

Fortunately, men who are suffering from Peyronie’s disease now have more treatment options available to them than ever before. While oral medications may not provide much benefit, new treatments like Xiaflex now provide men with another non-surgical option. For men who require surgery, options include plication, incision and grafting, and penile prosthesis placement. Although choice of treatment is highly dependent on multiple factors, each of these possibilities is designed to correct the underlying curvature and get you ‘back in the game’ as soon as possible.


Some Common Questions

Which treatment is right for me? This is a complex answer that depends on multiple factors, including the severity of the curvature and the presence of any pre-existing erectile dysfunction. It also depends on how long you’ve noticed the curvature. Men who are still in the ‘active’ phase of the disease may still develop increasing curvature and should not be treated until their curvature has stabilized. There are many reasons why men may be a better candidate for one procedure over another and the choice between these should be a shared decision-making process between you and your surgeon.


What if I don’t want surgery? Fortunately, every surgery for Peyronie’s disease is minimally invasive and does not require hospitalization afterwards. But for those men who qualify and still wish to avoid surgery, Xiaflex is an excellent option. A series of injections performed over several weeks, Xiaflex softens the scar tissue that causes Peyronie’s, gradually allowing the penis to straighten over time.